N-hydroxysuccinimide-ammonium salt → HCID 178486534, compound

Reaction equation

[C:1]([CH2:4][C:5]1[CH:32]=[CH:31][C:8]([NH:9]/[C:10](=[C:17]2\[C:18](=[O:30])[NH:19][C:20]3[C:25]\2=[CH:24][C:23]([O:26][CH3:27])=[C:22]([O:28][CH3:29])[CH:21]=3)/[C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[CH:7][CH:6]=1)(O)=[O:2].[NH4+].O[N:35]1C(=O)CCC1=O>>[NH2:35][C:1]([CH2:4][C:5]1[CH:6]=[CH:7][C:8]([NH:9]/[C:10](=[C:17]2\[C:18](=[O:30])[NH:19][C:20]3[C:25]\2=[CH:24][C:23]([O:26][CH3:27])=[C:22]([O:28][CH3:29])[CH:21]=3)/[C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[CH:31][CH:32]=1)=[O:2]

Participants

Reactant 2

HCID 22419393N-hydroxysuccinimide-ammonium salt

HCID 178486535CID 22668596

Product 1

HCID 178486534HCID 178486534, compound

Procedure

Prepared from 3-(Z)-(1-[4-(carboxymethyl)-anilino]-1-phenyl-methylidene)-5,6-dimethoxy-2-indolinone and N-hydroxy-succinimide-ammonium salt

Sources & evidence

ORD record: ord-1125121948ae43f4b34e8a13c48b4a40
Source dataset: uspto-grants-2004_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06794395B1

Reaction notes

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