Water → 1,2-Cyclohexanediol, 4-ethenyl-
Reaction equation
[CH2:1]=[CH:2][CH:3]1[CH2:8][CH:7]2[O:9][CH:6]2[CH2:5][CH2:4]1.O.S(=O)(=O)(O)[OH:12]>CC(C)=O>[OH:9][CH:6]1[CH2:5][CH2:4][CH:3]([CH:2]=[CH2:1])[CH2:8][CH:7]1[OH:12]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
Into a two-neck flask (100 ml) were fed 15.9 g (128 mmol) of 4-vinylcyclohexene-1,2-epoxide, 40 ml of water, 20 ml of acetone, and 40 μl of sulfuric acid, and the reaction mixture was refluxed at 75° C. for 4 hours. After complete reaction, an object compound was extracted with each 60 ml of diethylether four times, and was washed with saturated salt solution, and then was dried with sodium sulfate. The solvent was evaporated to obtain 1,2-dihydroxy-4-vinylcyclohexane.
Workup
- customInto a two-neck flask (100 ml) were fed
- customAfter complete reaction
- extractionan object compound was extracted with each 60 ml of diethylether four times
- washwas washed with saturated salt solution
- dry with materialwas dried with sodium sulfate
- customThe solvent was evaporated
Sources & evidence
- ORD record
- ord-d9c81395887b4a68a55f9994d3fb913c
- Source dataset
- uspto-grants-2004_09
- Patent number
- US06794528B2
Reaction notes
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