4-Chlorofuro[3,2-c]pyridine → Furo[3,2-c]pyridin-4-amine

HRID 1008552

Reaction equation

HRID 1008552 reaction equation
C[O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH:7]=[CH:8][N:9]=[C:10]2[NH2:13])=CC=1.ClC1C2C=COC=2C=CN=1>>[O:2]1[C:6]2[CH:7]=[CH:8][N:9]=[C:10]([NH2:13])[C:11]=2[CH:12]=[CH:3]1

Participants

3

Reactant 2

HCID 27797464-Chlorofuro[3,2-c]pyridineHCID 226656441-Isoquinolinamine, 7-methoxy-

Product 1

HCID 22665882Furo[3,2-c]pyridin-4-amine

Procedure

The procedure described to prepare 7-methoxyisoquinolin-1-ylamine was used to convert 15.3 g of 4-chloro-furo[3,2-c]pyridine into 12.2 g of the title compound as a brownish solid. m.p. 122-124° C.; EI-MS: 134 (M+).

Sources & evidence

ORD record
ord-75f1005977f34b05a6c3fd4cdf39db41
Source dataset
uspto-grants-2004_09
Patent number
US06797710B2

Linked notes

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