2-Amino-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → 5-[2-Fluoro-4-(2-hydroxypropan-2-yl)phenyl]-2-[[6-(2-methylmorpholine-4-carbonyl)-2-pyridinyl]amino]thiophene-3-carboxamide
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][cH:5][c:6]([C:8](=[O:9])[N:10]2[CH2:11][CH:12]([CH3:16])[O:13][CH2:14][CH2:15]2)[n:7]1.[NH2:17][c:18]1[s:19][c:20](-[c:26]2[c:27]([F:36])[cH:28][c:29]([C:32]([CH3:33])([CH3:34])[OH:35])[cH:30][cH:31]2)[cH:21][c:22]1[C:23](=[O:24])[NH2:25]>>[c:2]1([NH:17][c:18]2[s:19][c:20](-[c:26]3[c:27]([F:36])[cH:28][c:29]([C:32]([CH3:33])([CH3:34])[OH:35])[cH:30][cH:31]3)[cH:21][c:22]2[C:23](=[O:24])[NH2:25])[cH:3][cH:4][cH:5][c:6]([C:8](=[O:9])[N:10]2[CH2:11][CH:12]([CH3:16])[O:13][CH2:14][CH2:15]2)[n:7]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-3280069984ef4c0c87f2ff10049e728d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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