Thiopheneethanamine → Tert-butyl 2-[5-(2-thiophen-2-ylethylcarbamoyl)-3-pyridinyl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-5-carboxylate

HRID 101358Notes

Reaction equation

HRID 101358 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]2[CH:11]([CH2:12]1)[CH2:13][N:14]([c:16]1[cH:17][n:18][cH:19][c:20]([C:21](=[O:22])[OH:23])[cH:24]1)[CH2:15]2.[s:25]1[c:26]([CH2:30][CH2:31][NH2:32])[cH:27][cH:28][cH:29]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]2[CH:11]([CH2:12]1)[CH2:13][N:14]([c:16]1[cH:17][n:18][cH:19][c:20]([C:21](=[O:22])[NH:32][CH2:31][CH2:30][c:26]3[s:25][cH:29][cH:28][cH:27]3)[cH:24]1)[CH2:15]2

Participants

3

Reactant 2

HCID 116521ThiopheneethanamineHCID 671819795-[5-[(2-Methylpropan-2-yl)oxycarbonyl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-2-yl]pyridine-3-carboxylic acid

Product 1

HCID 67265651Tert-butyl 2-[5-(2-thiophen-2-ylethylcarbamoyl)-3-pyridinyl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-5-carboxylate

Sources & evidence

ORD record
ord-20712b21881544ea80d043e0ea7b4f15
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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