5-Nitroisoquinoline → 5-Nitro-1,2,3,4-tetrahydroisoquinoline
Reaction equation
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][N:8]=[CH:9]2)([O-:3])=[O:2].[BH4-].[Na+]>>[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH2:6][CH2:7][NH:8][CH2:9]2)([O-:3])=[O:2]Participants
3
Procedure
In close analogy to the procedure described above, 5-Nitro-isoquinoline is reacted with sodium borohydride to provide the title compound.
Sources & evidence
- ORD record
- ord-9b4a0e4ec5294467b1123a43cff239e8
- Source dataset
- uspto-grants-2011_07
- Patent number
- US07985753B2
Reaction notes
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