Acetic Anhydride → N-[2-(2,3-Dimethoxy-phenyl)-ethyl]-acetamide

HRID 1015024Notes

Reaction equation

[CH3:1][O:2][C:3]1[C:8]([O:9][CH3:10])=[CH:7][CH:6]=[CH:5][C:4]=1[CH2:11][CH2:12][NH2:13].[C:14](OC(=O)C)(=[O:16])[CH3:15]>>[CH3:1][O:2][C:3]1[C:8]([O:9][CH3:10])=[CH:7][CH:6]=[CH:5][C:4]=1[CH2:11][CH2:12][NH:13][C:14](=[O:16])[CH3:15]

Participants

Reactant 2

HCID 7918Acetic Anhydride

HCID 1378582,3-Dimethoxyphenethylamine

Product 1

HCID 47308767N-[2-(2,3-Dimethoxy-phenyl)-ethyl]-acetamide

Procedure

In close analogy to the procedure described above, 2-(2,3-dimethoxy-phenyl)-ethylamine is reacted with acetic anhydride to provide the title compound.

Sources & evidence

ORD record: ord-a76accca91f04142875d185c5be59ec9
Source dataset: uspto-grants-2011_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07985753B2

Reaction notes

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