Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 101770Generated: October 27, 2026

1-[2-(2-Hydroxyethoxy)ethyl]piperazine → 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-{2-[2-(1-piperazinyl)-ethoxy]ethoxy)-3-quinolinecarbonitrile

https://huagongshe.com/reaction/101770

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[2-(2-Hydroxyethoxy)ethyl]piperazineHCID 139436—
ReactantSodiumHCID 5360545—
Reactant4-[(2,4-Dichloro-5-methoxyphenyl)amino]-7-fluoro-6-methoxy-3-quinolinecarbonitrileHCID 11486153—
Product4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-{2-[2-(1-piperazinyl)-ethoxy]ethoxy)-3-quinolinecarbonitrileHCID 10460102—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-082eb0a2758044fa915a2ccc7b234f09
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)