4-Methoxy-N-[2,2,4,6,7-pentamethyl-3-(4-methylphenyl)-2,3-dihydro-1-benzofuran-5-yl]benzamide → N-(4-Methoxybenzyl)-2,2,4,6,7-pentamethyl-3-(4-methylphenyl)-2,3-dihydro-1-benzofuran-5-amine

HRID 1017898

Reaction equation

HRID 1017898 reaction equation
[CH3:1][O:2][C:3]1[CH:32]=[CH:31][C:6]([C:7]([NH:9][C:10]2[C:11]([CH3:30])=[C:12]([CH3:29])[C:13]3[O:17][C:16]([CH3:19])([CH3:18])[CH:15]([C:20]4[CH:25]=[CH:24][C:23]([CH3:26])=[CH:22][CH:21]=4)[C:14]=3[C:27]=2[CH3:28])=O)=[CH:5][CH:4]=1>C(O)C>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([CH2:7][NH:9][C:10]2[C:11]([CH3:30])=[C:12]([CH3:29])[C:13]3[O:17][C:16]([CH3:19])([CH3:18])[CH:15]([C:20]4[CH:21]=[CH:22][C:23]([CH3:26])=[CH:24][CH:25]=4)[C:14]=3[C:27]=2[CH3:28])=[CH:31][CH:32]=1

Participants

3

Reactant 1

HCID 102245694-Methoxy-N-[2,2,4,6,7-pentamethyl-3-(4-methylphenyl)-2,3-dihydro-1-benzofuran-5-yl]benzamide

Product 1

HCID 9801965N-(4-Methoxybenzyl)-2,2,4,6,7-pentamethyl-3-(4-methylphenyl)-2,3-dihydro-1-benzofuran-5-amineYield 58%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

By using 4-methoxy-N-[2,2,4,6,7-pentamethyl-3-(4-methylphenyl)-2,3-dihydro-1-benzofuran-5-yl]benzamide, the title compound was synthesized according to Example 2b. Yield: 58%. Melting point: 97-98° C. (Ethanol)

Sources & evidence

ORD record
ord-b334102b5d7d492e94083b240a47dd6f
Source dataset
uspto-grants-2002_11
Patent number
US06479536B1

Linked notes

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