(1,5-Dimethyl-1H-Pyrazol-3-Yl)Methanol → HCID 18401676, compound

HRID 1018616

Reaction equation

HRID 1018616 reaction equation
[F:1][C:2]([F:35])([F:34])[C:3]1[CH:4]=[C:5]([CH:27]=[C:28]([C:30]([F:33])([F:32])[F:31])[CH:29]=1)[C:6]([N:8]1[CH2:26][CH2:25][C:11]2([N:15]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=3[Cl:22])[C:14](=[O:23])[NH:13][C:12]2=[O:24])[CH2:10][CH2:9]1)=[O:7].[CH3:36][N:37]1[C:41]([CH3:42])=[CH:40][C:39]([CH2:43]O)=[N:38]1>>[F:35][C:2]([F:1])([F:34])[C:3]1[CH:4]=[C:5]([CH:27]=[C:28]([C:30]([F:32])([F:31])[F:33])[CH:29]=1)[C:6]([N:8]1[CH2:9][CH2:10][C:11]2([N:15]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=3[Cl:22])[C:14](=[O:23])[N:13]([CH2:43][C:39]3[CH:40]=[C:41]([CH3:42])[N:37]([CH3:36])[N:38]=3)[C:12]2=[O:24])[CH2:25][CH2:26]1)=[O:7]

Participants

3

Reactant 2

HCID 2776366(1,5-Dimethyl-1H-Pyrazol-3-Yl)MethanolHCID 18401685HCID 18401685, compound

Product 1

HCID 18401676HCID 18401676, compound

Procedure

The title compound, MS: m/e=627.1 (M+), was prepared in accordance with the general method of example 121 from 8-(3,5-bis-trifluoromethyl-benzoyl)-1-(2-chloro-phenyl)-1,3,8-triaza-spiro[4.5]decane-2,4-dione and 1,5 -dimethylpyrazole-3-methanol.

Sources & evidence

ORD record
ord-b82c1acfa0b2455b90a2669f3bf03dc0
Source dataset
uspto-grants-2002_11
Patent number
US06482829B2

Linked notes

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