Dichloromethane → 4-{[(3-Methyl-pyridin-2-ylmethyl)-amino]-methyl}-piperidine-1-carboxylic acid tert-butyl ester

HRID 101870Notes

Reaction equation

HRID 101870 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([CH:14]=[O:15])[CH2:12][CH2:13]1.[CH3:16][c:17]1[c:18]([CH2:23][NH2:24])[n:19][cH:20][cH:21][cH:22]1.[Cl:25][CH2:26][Cl:27]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([CH2:14][NH:24][CH2:23][c:18]2[c:17]([CH3:16])[cH:22][cH:21][cH:20][n:19]2)[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 1514370(3-Methylpyridin-2-yl)methanamineHCID 1514430tert-Butyl 4-formylpiperidine-1-carboxylate

Product 1

HCID 672717514-{[(3-Methyl-pyridin-2-ylmethyl)-amino]-methyl}-piperidine-1-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-819b341254e9463b88ad7f2e0900ce51
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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