Potassium Hydroxide → HCID 6992145, compound
Reaction equation
[C:1]1([C:7]2[C:16]3[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=3)[C:10]([SH:17])=[N:9][N:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[OH-].[K+].[Cl:20][C:21]1[CH:22]=[C:23]([CH:26]=[CH:27][CH:28]=1)[CH2:24]Br>C(O)C>[Cl:20][C:21]1[CH:22]=[C:23]([CH:26]=[CH:27][CH:28]=1)[CH2:24][S:17][C:10]1[C:11]2[C:16](=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)=[N:8][N:9]=1Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
To a suspension of 4-phenylphthalazine-1-thiol (1 mmol; from Example 1B) in ethanol (20 ml) is added aqueous KOH (1 molar;1 ml), and the mixture is stirred for 10 minutes to give a clear solution. 3-Chlorobenzylbromide (0.13 ml, 1 mmol) is added at room temperature, and the solution is stirred overnight. Work-up yields the title compound as a white solid (40 mg).