4-(O-Benzylhydroxylamino)-3-chloro-2-ethylpyridine → 4-[O-Benzyl-N-(spiro[5.5]undecan-3-yl)hydroxylamino]-3-chloro-2-ethylpyridine

HRID 1019

Reaction equation

HRID 1019 reaction equation
[CH2:1]([O:8][NH:9][C:10]1[CH:15]=[CH:14][N:13]=[C:12]([CH2:16][CH3:17])[C:11]=1[Cl:18])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.S(O[CH:30]1[CH2:35][CH2:34][C:33]2([CH2:40][CH2:39][CH2:38][CH2:37][CH2:36]2)[CH2:32][CH2:31]1)(C1C=CC(C)=CC=1)(=O)=O>>[CH2:1]([O:8][N:9]([C:10]1[CH:15]=[CH:14][N:13]=[C:12]([CH2:16][CH3:17])[C:11]=1[Cl:18])[CH:38]1[CH2:39][CH2:40][C:33]2([CH2:34][CH2:35][CH2:30][CH2:31][CH2:32]2)[CH2:36][CH2:37]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 196939374-(O-Benzylhydroxylamino)-3-chloro-2-ethylpyridineHCID 196940443-Tosyloxyspiro[5.5]undecane

Product 1

HCID 196939624-[O-Benzyl-N-(spiro[5.5]undecan-3-yl)hydroxylamino]-3-chloro-2-ethylpyridineYield 95%

Procedure

Was prepared analogously to Example 7 from 4-(O-benzylhydroxylamino)-3-chloro-2-ethylpyridine (Example 52) and 3-tosyloxyspiro[5.5]undecane. Yield: 95%

Sources & evidence

ORD record
ord-aef921fb8b7c405c92fb8244dd4e6640
Source dataset
uspto-grants-1998_03
Patent number
US05723450

Linked notes

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