6-Chloro-2-(trifluoromethyl)pyrimidin-4-amine → 6-(2-Fluoropyridin-3-yl)-2-(trifluoromethyl)pyrimidin-4-amine

HRID 102011

Reaction equation

HRID 102011 reaction equation
[Cl:11][c:12]1[cH:13][c:14]([NH2:22])[n:15][c:16]([C:18]([F:19])([F:20])[F:21])[n:17]1.[F:1][c:2]1[n:3][cH:4][cH:5][cH:6][c:7]1[B:8]([OH:9])[OH:10]>>[F:1][c:2]1[n:3][cH:4][cH:5][cH:6][c:7]1-[c:12]1[cH:13][c:14]([NH2:22])[n:15][c:16]([C:18]([F:19])([F:20])[F:21])[n:17]1

Participants

3

Reactant 2

HCID 2452716-Chloro-2-(trifluoromethyl)pyrimidin-4-amineHCID 27832702-Fluoropyridine-3-boronic acid

Product 1

HCID 665999396-(2-Fluoropyridin-3-yl)-2-(trifluoromethyl)pyrimidin-4-amine

Sources & evidence

ORD record
ord-d3e87478100545f288a4c03f61533694
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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