HCID 59355188, compound → HCID 59355176, compound
Reaction equation
[CH3:1][N:2]([CH3:13])[CH2:3][CH2:4][NH:5][CH2:6][C:7]([CH3:12])([N+:9]([O-])=O)[CH3:8]>CO.[Ni].O>[CH3:13][N:2]([CH3:1])[CH2:3][CH2:4][NH:5][CH2:6][C:7]([CH3:8])([NH2:9])[CH3:12]Participants
5
Reactant 1
Product 1
Reagents, catalysts & solvents 3
Procedure
To a solution of N1,N1-dimethyl-N2-(2-methyl-2-nitropropyl)ethane-1,2-diamine (23.2 mmol) in MeOH (20 ml) was added a slurry of Raney Nickel in H2O (1 ml). The vessel was pressurized with H2 (500 psi) and the suspension stirred for 24 h. The mixture was filtered through Celite, then 0.45 um PTFE, and concentrated in vacuo. ESI/APCI (pos) expected for C8H21N3: 159.17. Found: 160 (MH+).
Workup
- filtrationThe mixture was filtered through Celite
- concentration0.45 um PTFE, and concentrated in vacuo
Sources & evidence
- ORD record
- ord-05cc1d1f75f842389e569eb09d38a6cb
- Source dataset
- uspto-grants-2014_05
- Patent number
- US08722715B2
Reaction notes
Loading…