Sodium ion → 4-Methyl-2-[(2-methyl-1,3-thiazol-4-yl)methyl]-8-(1-propan-2-ylpiperidin-4-yl)oxy-3,4-dihydropyrazino[1,2-a]indol-1-one

HRID 102704

Reaction equation

HRID 102704 reaction equation
[CH:1]([CH3:2])([CH3:3])[N:4]1[CH2:5][CH2:6][CH:7]([O:10][c:11]2[cH:12][c:13]3[cH:14][c:15]4[n:16]([c:17]3[cH:18][cH:19]2)[CH:20]([CH3:25])[CH2:21][NH:22][C:23]4=[O:24])[CH2:8][CH2:9]1.[Cl:28][CH2:29][c:30]1[n:31][c:32]([CH3:35])[s:33][cH:34]1.[H-:26].[Na+:27]>>[CH:1]([CH3:2])([CH3:3])[N:4]1[CH2:5][CH2:6][CH:7]([O:10][c:11]2[cH:12][c:13]3[cH:14][c:15]4[n:16]([c:17]3[cH:18][cH:19]2)[CH:20]([CH3:25])[CH2:21][N:22]([CH2:29][c:30]2[n:31][c:32]([CH3:35])[s:33][cH:34]2)[C:23]4=[O:24])[CH2:8][CH2:9]1

Participants

5

Reactant 4

HCID 923Sodium ionHCID 166653HydrideHCID 7363414-(Chloromethyl)-2-methyl-1,3-thiazoleHCID 684633554-methyl-8-(1-propan-2-ylpiperidin-4-yl)oxy-3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one

Product 1

HCID 684647744-Methyl-2-[(2-methyl-1,3-thiazol-4-yl)methyl]-8-(1-propan-2-ylpiperidin-4-yl)oxy-3,4-dihydropyrazino[1,2-a]indol-1-one

Sources & evidence

ORD record
ord-f64b6fc3f22945ef92af82600c31cf9d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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