Ethanol → 6-(3,4-Difluorophenyl)-2-naphthol

HRID 102754

Reaction equation

HRID 102754 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[cH:5][cH:6][c:7]([OH:12])[cH:8][c:9]2[cH:10][cH:11]1.[C:32](=[O:33])([O-:34])[O-:35].[CH3:115][CH2:116][OH:117].[CH3:25][c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1.[F:13][c:14]1[cH:15][c:16]([O:21][B:22]([OH:23])[OH:24])[cH:17][cH:18][c:19]1[F:20].[K+:36].[K+:37].[cH:38]1[cH:39][cH:40][c:41]([P:42]([Pd:43]([P:44]([c:45]2[cH:46][cH:47][cH:48][cH:49][cH:50]2)([c:51]2[cH:52][cH:53][cH:54][cH:55][cH:56]2)[c:57]2[cH:58][cH:59][cH:60][cH:61][cH:62]2)([P:63]([c:64]2[cH:65][cH:66][cH:67][cH:68][cH:69]2)([c:70]2[cH:71][cH:72][cH:73][cH:74][cH:75]2)[c:76]2[cH:77][cH:78][cH:79][cH:80][cH:81]2)[P:82]([c:83]2[cH:84][cH:85][cH:86][cH:87][cH:88]2)([c:89]2[cH:90][cH:91][cH:92][cH:93][cH:94]2)[c:95]2[cH:96][cH:97][cH:98][cH:99][cH:100]2)([c:101]2[cH:102][cH:103][cH:104][cH:105][cH:106]2)[c:107]2[cH:108][cH:109][cH:110][cH:111][cH:112]2)[cH:113][cH:114]1>>[c:2]1(-[c:16]2[cH:15][c:14]([F:13])[c:19]([F:20])[cH:18][cH:17]2)[cH:3][c:4]2[cH:5][cH:6][c:7]([OH:12])[cH:8][c:9]2[cH:10][cH:11]1

Participants

8

Reactant 7

HCID 702EthanolHCID 813Potassium Cation2×HCID 1140TolueneHCID 19660Carbonate IonHCID 271446-Bromo-2-naphthalenolHCID 218696723,4-Difluorophenylboric acidHCID 178420554HCID 178420554, compound

Product 1

HCID 218708206-(3,4-Difluorophenyl)-2-naphthol

Sources & evidence

ORD record
ord-f72c73294b874a72874ef34915aff37c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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