Water → N-benzyl-4-[2-(difluoromethyl)-1H-benzimidazol-1-yl]-6-(4-morpholinyl)-1,3,5-triazin-2-amine

HRID 102973

Reaction equation

HRID 102973 reaction equation
[Cl:1][c:2]1[n:3][c:4](-[n:14]2[c:15]([CH:23]([F:24])[F:25])[n:16][c:17]3[c:18]2[cH:19][cH:20][cH:21][cH:22]3)[n:5][c:6]([N:8]2[CH2:9][CH2:10][O:11][CH2:12][CH2:13]2)[n:7]1.[NH2:26][CH2:27][c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1.[O:34]1[CH2:35][CH2:36][O:37][CH2:38][CH2:39]1.[OH2:40]>>[c:2]1([NH:26][CH2:27][c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)[n:3][c:4](-[n:14]2[c:15]([CH:23]([F:24])[F:25])[n:16][c:17]3[c:18]2[cH:19][cH:20][cH:21][cH:22]3)[n:5][c:6]([N:8]2[CH2:9][CH2:10][O:11][CH2:12][CH2:13]2)[n:7]1

Participants

5

Reactant 4

HCID 962WaterHCID 7504BenzylamineHCID 312751,4-DioxaneHCID 220368724-(4-chloro-6-(2-(difluoromethyl)-1H-benzo[d]imidazol-1-yl)-1,3,5-triazin-2-yl)morpholine

Product 1

HCID 49868946N-benzyl-4-[2-(difluoromethyl)-1H-benzimidazol-1-yl]-6-(4-morpholinyl)-1,3,5-triazin-2-amine

Sources & evidence

ORD record
ord-30c8904247d34c10903bee3dca3ffa00
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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