Acetic Anhydride → HCID 54366097, compound

Reaction equation

[CH3:1][N:2]1[C:6]2[CH:7]=[C:8]([C:14]([OH:16])=[O:15])[C:9]([C:11](O)=[O:12])=[CH:10][C:5]=2[N:4]=[C:3]1[CH3:17].C(OC(=O)C)(=O)C>>[CH3:1][N:2]1[C:6]2[CH:7]=[C:8]3[C:14](=[O:16])[O:15][C:11](=[O:12])[C:9]3=[CH:10][C:5]=2[N:4]=[C:3]1[CH3:17]

Participants

Reactant 2

HCID 7918Acetic Anhydride

HCID 22402945HCID 22402945, compound

Product 1

HCID 54366097HCID 54366097, compoundYield 90.1%

Procedure

A mixture of the 1,2-dimethyl-5,6-benzimidazoledicarboxylic acid (1.25 g, 5.34 mmol) and acetic anhydride is stirred for 2 hours at reflux temperature, cooled to 5 ° and filtered The filter cake is dried to give the title product as brown needles (1.04 g, 90.1%), mp 310°-315° C.

Workup

temperatureat reflux temperature
temperaturecooled to 5 °
filtrationfiltered The filter cake
customis dried

Sources & evidence

ORD record: ord-b41d1a1daf50446b8cfe8fb2850553c7
Source dataset: uspto-grants-1992_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05108485

Reaction notes

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