Diethyl Ether → 2-(N-methyl-N-(methoxycarbonyl)amino)-4'-propoxyacetophenone
Reaction equation
[CH3:1][N:2]([CH2:7][C:8]([C:10]1[CH:15]=[CH:14][C:13]([O:16][CH:17](F)F)=[CH:12][CH:11]=1)=[O:9])[C:3]([O:5][CH3:6])=[O:4].[CH2:20](OCC)[CH3:21]>>[CH3:1][N:2]([CH2:7][C:8]([C:10]1[CH:15]=[CH:14][C:13]([O:16][CH2:17][CH2:20][CH3:21])=[CH:12][CH:11]=1)=[O:9])[C:3]([O:5][CH3:6])=[O:4]Participants
3
Procedure
By substantially following the procedure given in Example 19b, substituting 2-(N-methyl-N-(methoxycarbonyl)amino)-4'-propoxyacetophenone for 2-(N-methyl-N-(methoxycarbonyl)amino)-4'-difluoromethoxyacetophenone and using diethyl ether as solvent and continuing with Example 19dii the expected compound, an oil, bp 150°-160° C. at 0.2 torr, was obtained.
Sources & evidence
- ORD record
- ord-be85aa39c7c34273b5ee1e085c23ba7b
- Source dataset
- uspto-grants-1992_04