Acetate → ethyl [(trans-4-{6-[1-(2'-cyanobiphenyl-4-yl)ethyl]-5-oxo-7-propyl[1,2,4]triazolo[1,5-a]pyrimidin-4(5H)-yl}cyclohexyl)oxy]acetate

HRID 103133

Reaction equation

HRID 103133 reaction equation
[C:53]([O-:54])(=[O:55])[CH3:56].[CH3:46][c:47]1[cH:48][cH:49][cH:50][cH:51][cH:52]1.[N+:37](=[N-:38])=[CH:39][C:40](=[O:41])[O:42][CH2:43][CH3:44].[OH2:45].[OH:1][CH:2]1[CH2:3][CH2:4][CH:5]([n:8]2[c:9]3[n:10]([c:11]([CH2:31][CH2:32][CH3:33])[c:12]([CH:15]([CH3:16])[c:17]4[cH:18][cH:19][c:20](-[c:23]5[c:24]([C:29]#[N:30])[cH:25][cH:26][cH:27][cH:28]5)[cH:21][cH:22]4)[c:13]2=[O:14])[n:34][cH:35][n:36]3)[CH2:6][CH2:7]1.[Rh+:57]>>[O:1]([CH:2]1[CH2:3][CH2:4][CH:5]([n:8]2[c:9]3[n:10]([c:11]([CH2:31][CH2:32][CH3:33])[c:12]([CH:15]([CH3:16])[c:17]4[cH:18][cH:19][c:20](-[c:23]5[c:24]([C:29]#[N:30])[cH:25][cH:26][cH:27][cH:28]5)[cH:21][cH:22]4)[c:13]2=[O:14])[n:34][cH:35][n:36]3)[CH2:6][CH2:7]1)[CH2:39][C:40](=[O:41])[O:42][CH2:43][CH3:44]

Participants

7

Reactant 6

HCID 175AcetateHCID 962WaterHCID 1140TolueneHCID 12192Ethyl diazoacetateHCID 670104844'-{1-[4-(trans-4-Hydroxycyclohexyl)-5-oxo-7-propyl-4,5-dihydro[1,2,4]triazolo[1,5-a]pyrimidin-6-yl]ethyl}biphenyl-2-carbonitrileHCID 178527705HCID 178527705, compound

Product 1

HCID 86644076ethyl [(trans-4-{6-[1-(2'-cyanobiphenyl-4-yl)ethyl]-5-oxo-7-propyl[1,2,4]triazolo[1,5-a]pyrimidin-4(5H)-yl}cyclohexyl)oxy]acetate

Sources & evidence

ORD record
ord-1cf4874ef1f24f608b7af13eba7089a2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

Loading…