Ammonium → tert-butyl 4-(1H-pyrrolo[2,3-b]pyridin-3-yl)piperidine-1-carboxylate

Reaction equation

[CH3:27][CH2:28][OH:29].[CH:23]([O-:24])=[O:25].[NH4+:26].[nH:1]1[cH:2][c:3]([C:10]2=[CH:11][CH2:12][N:13]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:14][CH2:15]2)[c:4]2[c:5]1[n:6][cH:7][cH:8][cH:9]2>>[nH:1]1[cH:2][c:3]([CH:10]2[CH2:11][CH2:12][N:13]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:14][CH2:15]2)[c:4]2[c:5]1[n:6][cH:7][cH:8][cH:9]2

Participants

Reactant 4

HCID 223Ammonium

HCID 283Formate

HCID 702Ethanol

HCID 45790246Tert-butyl 4-(1H-pyrrolo[2,3-B]pyridin-3-YL)-5,6-dihydropyridine-1(2H)-carboxylate

Product 1

HCID 49758876tert-butyl 4-(1H-pyrrolo[2,3-b]pyridin-3-yl)piperidine-1-carboxylate

Sources & evidence

ORD record: ord-b71c191679aa442cbd70c9b999c76336
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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