HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 4-Benzyloxy-3-nitrobenzyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | (4-(Benzyloxy)-3-nitrophenyl)methanol | HCID 13629301 | — |
| Product | 4-Benzyloxy-3-nitrobenzyl chloride | HCID 13629302 | — |
Reaction Steps
Under agitation, 58.3 g of 4-benzyloxy-3-nitrobenzyl alcohol is introduced in incremental portions into 250 ml of thionyl chloride, stirred for 30 minutes at room temperature, and concentrated under vacuum. The residue is recrystallized from diisopropyl ether while decolorizing with active carbon, thus producing 50.9 g of 4-benzyloxy-3-nitrobenzyl chloride, mp 60°-61° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04958026 |
| Source dataset | uspto-grants-1990_09 |
| ORD ID | ord-f154fe0b6dc34555ac16b885a6de168a |
| Source note | uspto-grants-1990_09 |