Nitrous Acid → HCID 178451313, compound

Reaction equation

[Cl:1][CH2:2][C:3](=[O:12])[CH2:4][C:5]([O:7][C:8]([CH3:11])([CH3:10])[CH3:9])=[O:6].[N:13]([O-])=[O:14].[Na+].N(O)=O>>[Cl:1][CH2:2][C:3](=[O:12])/[C:4](=[N:13]/[OH:14])/[C:5]([O:7][C:8]([CH3:9])([CH3:11])[CH3:10])=[O:6]

Participants

Reactant 3

HCID 24529Nitrous Acid

HCID 2724514tert-Butyl 4-chloro-3-oxobutyrate

HCID 23668193Sodium Nitrite

Product 1

HCID 178451313HCID 178451313, compound

Procedure

treating t-butyl 4-chloro-3-oxobutanoate with sodium nitrite or nitrous acid to produce t-butyl 4-chloro-2-(Z)-hydroximino-3-oxobutanoate;

Sources & evidence

ORD record: ord-3e86ab751c5842fe86d5e66a0c172b5b
Source dataset: uspto-grants-1990_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04959495

Reaction notes

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