Hydrazine → 6,11-dihydro-5H-benzo[c][1]benzazepin-6-ylmethanamine

Reaction equation

C1(=O)[N:5]([CH2:6][CH:7]2[NH:13][C:12]3[CH:14]=[CH:15][CH:16]=[CH:17][C:11]=3[CH2:10][C:9]3[CH:18]=[CH:19][CH:20]=[CH:21][C:8]2=3)C(=O)C2=CC=CC=C12.NN>>[NH2:5][CH2:6][CH:7]1[NH:13][C:12]2[CH:14]=[CH:15][CH:16]=[CH:17][C:11]=2[CH2:10][C:9]2[CH:18]=[CH:19][CH:20]=[CH:21][C:8]1=2

Participants

Reactant 2

HCID 9321Hydrazine

HCID 99466272-((6,11-Dihydro-5H-dibenzo[b,e]azepin-6-yl)methyl)isoindoline-1,3-dione

Product 1

HCID 98778946,11-dihydro-5H-benzo[c][1]benzazepin-6-ylmethanamine

Procedure

reacting the 6-(phthalimidomethyl)-6,11-dihydro-5H-dibenz[b,e]azepine with hydrazine in an alkali metal hydroxide to produce 6-aminomethyl-6,11-dihydro-5H-dibenz[b,e]azepine;

Sources & evidence

ORD record: ord-6e3e1c9b05c746b7b159c0976b56c652
Source dataset: uspto-grants-1994_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05312916

Reaction notes

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