1-(2-Piperidino-phenyl)-1-butylamine → 2-Ethoxy-4-[N-{1-(2-piperidino-phenyl)-1-butyl}aminocarbonylmethyl]-toluene

Reaction equation

[N:1]1([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=2[CH:13]([NH2:17])[CH2:14][CH2:15][CH3:16])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH2:18]([O:20][C:21]1[CH:22]=[C:23]([CH2:28][C:29](O)=[O:30])[CH:24]=[CH:25][C:26]=1[CH3:27])[CH3:19]>>[CH2:18]([O:20][C:21]1[CH:22]=[C:23]([CH2:28][C:29]([NH:17][CH:13]([C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[N:1]2[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]2)[CH2:14][CH2:15][CH3:16])=[O:30])[CH:24]=[CH:25][C:26]=1[CH3:27])[CH3:19]

Participants

Reactant 2

HCID 134908841-(2-Piperidino-phenyl)-1-butylamine

HCID 212618973-Ethoxy-4-methyl-phenylacetic acid

Product 1

HCID 212617732-Ethoxy-4-[N-{1-(2-piperidino-phenyl)-1-butyl}aminocarbonylmethyl]-toluene

Procedure

Prepared from 1-(2-piperidino-phenyl)-1-butylamine and 3-ethoxy-4-methyl-phenylacetic acid.

Sources & evidence

ORD record: ord-a74de4c1712643cdb279c1398e90fd2d
Source dataset: uspto-grants-1994_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05312924

Reaction notes

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