Iodine chloride → 2,6-Difluoro-4-iodoaniline

HRID 1034102

Reaction equation

HRID 1034102 reaction equation

[F:1][C:2]1[CH:8]=[CH:7][CH:6]=[C:5]([F:9])[C:3]=1[NH2:4].[I:10]Cl>C(O)(=O)C>[F:1][C:2]1[CH:8]=[C:7]([I:10])[CH:6]=[C:5]([F:9])[C:3]=1[NH2:4]

Participants

4

Reactant 2

HCID 24640Iodine chloride

HCID 796472,6-Difluoroaniline

Product 1

HCID 2789432,6-Difluoro-4-iodoaniline

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

2,6-difluoroaniline (5) is reacted with iodine chloride in acetic acid to yield 2,6-difluoro-4-iodaniline (6).

Sources & evidence

ORD record: ord-045406f602144d1face873273bc33412
Source dataset: uspto-grants-1994_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05314640

Linked notes

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