HCID 10536240, compound → HCID 57899129, compound

Reaction equation

[CH2:1]([C:8]1([OH:15])[CH2:13][CH2:12][N:11]([CH3:14])[CH2:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.ClC1[N:25]=[CH:24][N:23]=[C:22]2[C:18]=1[NH:19][C:20](=[O:26])[NH:21]2>>[CH2:1]([C:8]1([OH:15])[CH2:13][CH2:12][N:11]([C:14]2[N:25]=[CH:24][N:23]=[C:22]3[C:18]=2[NH:19][C:20](=[O:26])[NH:21]3)[CH2:10][CH2:9]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

Reactant 2

HCID 10536240HCID 10536240, compound

HCID 576592036-chloro-8,9-dihydro-7H-purin-8-one

Product 1

HCID 57899129HCID 57899129, compound

Procedure

4-Benzyl-1-methyl-piperidin-4-ol was reacted with 6-chloro-7,9-dihydro-purin-8-one under conditions analogous to those set out in Example 3A to give the title compound LC/MS: (LCT) Rt 5.68 [M+H]+ 326.

Sources & evidence

ORD record: ord-b062b8fabd21453789bf33179c6dec4c
Source dataset: uspto-grants-2013_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08546407B2

Reaction notes

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