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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 103697Generated: October 27, 2026

Pyridine → N-[4,4,4-trifluoro-1-hydroxy-3-(trifluoromethyl)butan-2-yl]thiophene-3-sulfonamide

https://huagongshe.com/reaction/103697

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyridineHCID 1049—
Reactantp-Toluenesulfonic acidHCID 6101—
ReactantDichloromethaneHCID 6344—
ReactantEthyl AcetateHCID 8857—
ReactantThiophene-3-sulfonyl ChlorideHCID 2776378—
Reactant3,3,3-Trifluoro-2-(trifluoromethyl)-1-(hydroxymethyl)propylamineHCID 45107971—
ProductN-[4,4,4-trifluoro-1-hydroxy-3-(trifluoromethyl)butan-2-yl]thiophene-3-sulfonamideHCID 11428270—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-f42b394ca20844ce8ad92355858aeb51
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)