1,3-Dichloro-2-isocyanatobenzene → HCID 57710227, compound

Reaction equation

[CH3:1][O:2][C:3]1[N:8]=[CH:7][C:6]([NH:9][C:10]2[CH:15]=[C:14]([NH2:16])[N:13]=[CH:12][N:11]=2)=[CH:5][CH:4]=1.[Cl:17][C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([Cl:24])[C:19]=1[N:25]=[C:26]=[O:27]>>[Cl:17][C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([Cl:24])[C:19]=1[NH:25][C:26]([NH:16][C:14]1[CH:15]=[C:10]([NH:9][C:6]2[CH:7]=[N:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=2)[N:11]=[CH:12][N:13]=1)=[O:27]

Participants

Reactant 2

HCID 6045371,3-Dichloro-2-isocyanatobenzene

HCID 66669976HCID 66669976, compound

Product 1

HCID 57710227HCID 57710227, compound

Procedure

The title compound is prepared analogously as described in Example 105B from N-(6-methoxy-pyridin-3-yl)-pyrimidine-4,6-diamine and 2,6-dichlorophenyl isocyanate.

Sources & evidence

ORD record: ord-f87c90ad0e74415eaa3fc20e148a0c2d
Source dataset: uspto-grants-2013_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08552002B2

Reaction notes

Loading…