(R)-2-BOC-amino-3-(4-methoxy-benzylsulfanyl)-propionic acid → (R)-2-Amino-3-(4-methoxy-benzylsulfanyl)propionic acid methyl ester

HRID 1045836

Reaction equation

HRID 1045836 reaction equation
[C:1]([C@@:8]([NH2:23])([CH2:12][S:13][CH2:14][C:15]1[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=1)C(O)=O)([O:3][C:4](C)(C)C)=[O:2]>CO>[CH3:4][O:3][C:1](=[O:2])[C@@H:8]([NH2:23])[CH2:12][S:13][CH2:14][C:15]1[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=1

Participants

3

Reactant 1

HCID 68486000(R)-2-BOC-amino-3-(4-methoxy-benzylsulfanyl)-propionic acid

Product 1

HCID 14390800(R)-2-Amino-3-(4-methoxy-benzylsulfanyl)propionic acid methyl ester

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

(R)-2-BOC-amino-3-(4-methoxy-benzylsulfanyl)-propionic acid prepared in Step B of Preparation 27 and methanol were reacted according to the same procedure as Preparation 30 to give the title compound.

Workup

  1. customwere reacted
  2. customaccording to the same procedure as Preparation 30

Sources & evidence

ORD record
ord-5c38a89ea34b4005a18362e05e865073
Source dataset
uspto-grants-2013_10
Patent number
US08569307B2

Linked notes

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