2-Propylthiazole → 2-(1-Bromopropyl)thiazole

Reaction equation

[CH2:1]([C:4]1[S:5][CH:6]=[CH:7][N:8]=1)[CH2:2][CH3:3].[Br:9]C(C1C=CC=CN=1)CC>>[Br:9][CH:1]([C:4]1[S:5][CH:6]=[CH:7][N:8]=1)[CH2:2][CH3:3]

Participants

Reactant 2

HCID 871982-Propylthiazole

HCID 576566272-(1-Bromopropyl)pyridine

Product 1

HCID 585733632-(1-Bromopropyl)thiazole

Procedure

The title compound was prepared from 2-propylthiazole (purchased from Waterstone Technologies, Inc., Carmel, Ind.) following a procedure similar to the one described above for the synthesis of 2-(1-bromopropyl)pyridine (Example 230). Mass Spectrum (ESI) m/z=205.8 and 207.8 (M+1).

Sources & evidence

ORD record: ord-6d179721ff3c4c74b7463dbab9c5b419
Source dataset: uspto-grants-2013_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08569341B2

Reaction notes

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