Water → Apomorphine

HRID 1048683

Reaction equation

HRID 1048683 reaction equation
[CH3:1][N:2]1[C@@H:11]2[CH2:12][C:13]3[CH:18]=[CH:17][C:16]([OH:19])=[C:15]([OH:20])[C:14]=3[C:9]3[C:10]2=[C:5]([CH:6]=[CH:7][CH:8]=3)[CH2:4][CH2:3]1.O.[NH2:22][C@H:23]([C:28]([OH:30])=[O:29])[CH2:24][C:25]([OH:27])=[O:26]>>[CH3:1][N:2]1[C@@H:11]2[CH2:12][C:13]3[CH:18]=[CH:17][C:16]([OH:19])=[C:15]([OH:20])[C:14]=3[C:9]3[C:10]2=[C:5]([CH:6]=[CH:7][CH:8]=3)[CH2:4][CH2:3]1.[NH2:22][C@H:23]([C:28]([O-:30])=[O:29])[CH2:24][C:25]([O-:27])=[O:26].[CH3:1][N:2]1[C@@H:11]2[CH2:12][C:13]3[CH:18]=[CH:17][C:16]([OH:19])=[C:15]([OH:20])[C:14]=3[C:9]3[C:10]2=[C:5]([CH:6]=[CH:7][CH:8]=3)[CH2:4][CH2:3]1

Participants

5

Reactant 3

HCID 962WaterHCID 5960L-Aspartic AcidHCID 6005Apomorphine

Product 2

HCID 6005ApomorphineHCID 131735989Apomorphine aspartate

Procedure

Apomorphine aspartate solution was prepared by dissolving apomorphine base in 0.1M aspartic acid solution. Water was added to obtain a molar ratio of 1:1, apomorphine:aspartic acid, at a final concentration of 2% apomorphine. The pH of the solution was 4.9.

Sources & evidence

ORD record
ord-e45f19d0f1a442fdbd9926dcfa5fb11c
Source dataset
uspto-grants-2016_07
Patent number
US09381249B2

Linked notes

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