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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 105355Generated: October 27, 2026

Hydrochloric Acid → N-[(2-chloro-4-fluorophenyl)methyl]-1-ethyl-4,4-dimethyl-5-oxopyrrolidine-2-carboxamide

https://huagongshe.com/reaction/105355

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantDichloromethaneHCID 6344—
Reactant1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 15908—
Reactant1-HydroxybenzotriazoleHCID 75771—
ReactantDiisopropylethylamineHCID 81531—
Reactant2-Chloro-4-fluorobenzylamineHCID 139909—
Reactant1-Ethyl-4,4-dimethyl-5-oxopyrrolidine-2-carboxylic acidHCID 67461588—
ProductN-[(2-chloro-4-fluorophenyl)methyl]-1-ethyl-4,4-dimethyl-5-oxopyrrolidine-2-carboxamideHCID 59303313—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-0b3476ae892247e8933179aa42cac627
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)