Potassium Cation → N-(1-(3-fluoro-4-methoxyphenyl)-5-oxopyrrolidin-3-yl)benzamide

Reaction equation

[C:23]([c:24]1[cH:25][cH:26][cH:27][cH:28][cH:29]1)(=[O:30])[Cl:31].[Cl:32][CH2:33][Cl:34].[K+:17].[K+:18].[NH2:1][CH:2]1[CH2:3][C:4](=[O:16])[N:5]([c:7]2[cH:8][c:9]([F:15])[c:10]([O:13][CH3:14])[cH:11][cH:12]2)[CH2:6]1.[O-:19][C:20]([O-:21])=[O:22]>>[NH:1]([CH:2]1[CH2:3][C:4](=[O:16])[N:5]([c:7]2[cH:8][c:9]([F:15])[c:10]([O:13][CH3:14])[cH:11][cH:12]2)[CH2:6]1)[C:23]([c:24]1[cH:25][cH:26][cH:27][cH:28][cH:29]1)=[O:30]

Participants

Reactant 5

HCID 813Potassium Cation2×

HCID 6344Dichloromethane

HCID 7412Benzoyl chloride

HCID 19660Carbonate Ion

HCID 435211184-Amino-1-(3-fluoro-4-methoxyphenyl)pyrrolidin-2-one

Product 1

HCID 68419077N-(1-(3-fluoro-4-methoxyphenyl)-5-oxopyrrolidin-3-yl)benzamide

Sources & evidence

ORD record: ord-1b2f5edfc2954e0094a52829be1cb5bb
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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