N1,N1-Dibenzylethane-1,2-diamine → Benzathine

HRID 1057393Notes

Reaction equation

HRID 1057393 reaction equation
C([N:8]([CH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[CH2:9][CH2:10][NH2:11])C1C=CC=CC=1>O>[CH:16]1[CH:17]=[CH:18][C:13]([CH2:12][NH:11][CH2:10][CH2:9][NH:8][CH2:12][C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=2)=[CH:14][CH:15]=1

Participants

3

Reactant 1

HCID 6394114N1,N1-Dibenzylethane-1,2-diamine

Product 1

HCID 8793Benzathine

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

HPLC analysis shows there to be 19.7% N,N dibenzylethylenediamine and 80% compound of Example 42 to be present by total area analysis. Water is present at 0.3%. This gives a stoichiometric ratio of compound to base of 1:0:5.

Workup

  1. customThis gives a stoichiometric ratio of compound to base of 1:0:5

Sources & evidence

ORD record
ord-dd6d9e155ecc4ebfb89127bc8f8219c4
Source dataset
uspto-grants-2003_02
Patent number
US06514975B1

Reaction notes

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