Ethylboronic acid → N-(4-tert-butyl-benzyl)-3-chloro-N-[2-(3-ethyl-4-fluoro-phenyl)-ethyl]-2-fluoro-5-trifluoromethyl-benzamide

HRID 105827

Reaction equation

HRID 105827 reaction equation
[Br:1][c:2]1[cH:3][c:4]([CH2:9][CH2:10][N:11]([C:12]([c:13]2[c:14]([F:24])[c:15]([Cl:23])[cH:16][c:17]([C:19]([F:20])([F:21])[F:22])[cH:18]2)=[O:25])[CH2:26][c:27]2[cH:28][cH:29][c:30]([C:33]([CH3:34])([CH3:35])[CH3:36])[cH:31][cH:32]2)[cH:5][cH:6][c:7]1[F:8].[CH2:37]([CH3:38])[B:39]([OH:40])[OH:41]>>[c:2]1([CH2:37][CH3:38])[cH:3][c:4]([CH2:9][CH2:10][N:11]([C:12]([c:13]2[c:14]([F:24])[c:15]([Cl:23])[cH:16][c:17]([C:19]([F:20])([F:21])[F:22])[cH:18]2)=[O:25])[CH2:26][c:27]2[cH:28][cH:29][c:30]([C:33]([CH3:34])([CH3:35])[CH3:36])[cH:31][cH:32]2)[cH:5][cH:6][c:7]1[F:8]

Participants

3

Reactant 2

HCID 521157Ethylboronic acidHCID 86613996N-[2-(3-bromo-4-fluoro-phenyl)-ethyl]-N-(4-tert-butyl-benzyl)-3-chloro-2-fluoro-5-trifluoromethyl-benzamide

Product 1

HCID 86613995N-(4-tert-butyl-benzyl)-3-chloro-N-[2-(3-ethyl-4-fluoro-phenyl)-ethyl]-2-fluoro-5-trifluoromethyl-benzamide

Sources & evidence

ORD record
ord-359134c3d15f49b2b0b92781d3403ac6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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