Pyridinium chloride → HCID 178457680, compound
Reaction equation
[OH:1][C:2]([C:30]1[CH:35]=[CH:34][C:33]([C:36]2[CH:41]=[CH:40][CH:39]=[C:38]([C:42]([NH:44][CH:45]([CH3:47])[CH3:46])=[O:43])[CH:37]=2)=[CH:32][CH:31]=1)([C:6]1[N:7]=[CH:8][N:9](C(C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[CH:10]=1)[CH:3]([CH3:5])[CH3:4].Cl.N1C=CC=CC=1>>[OH:1][C:2]([C:30]1[CH:31]=[CH:32][C:33]([C:36]2[CH:41]=[CH:40][CH:39]=[C:38]([C:42]([NH:44][CH:45]([CH3:47])[CH3:46])=[O:43])[CH:37]=2)=[CH:34][CH:35]=1)([C:6]1[N:7]=[CH:8][NH:9][CH:10]=1)[CH:3]([CH3:5])[CH3:4]Participants
3
Procedure
By the reaction in the same manner as in Example 4-(iii) using 4′-[1-hydroxy-2-methyl-1-(1-trityl-1H-imidazol-4-yl)propyl]-N-isopropyl[1,1′-biphenyl]-3-carboxamide (1.67 g) and pyridine hydrochloride (490 mg), the title compound (480 mg) was obtained as colorless powder crystals.
Workup
- customBy the reaction in the same manner as in Example
Sources & evidence
- ORD record
- ord-606a264bb5be4df2baa39651da93ecab