2-Furancarbonyl chloride → N-(4,6-difluoro-1,3-benzothiazol-2-yl)furan-2-carboxamide

HRID 1060264

Reaction equation

HRID 1060264 reaction equation
[NH2:1][C:2]1[S:3][C:4]2[CH:10]=[C:9]([F:11])[CH:8]=[C:7]([F:12])[C:5]=2[N:6]=1.[O:13]1[CH:17]=[CH:16][CH:15]=[C:14]1[C:18](Cl)=[O:19]>>[F:12][C:7]1[C:5]2[N:6]=[C:2]([NH:1][C:18]([C:14]3[O:13][CH:17]=[CH:16][CH:15]=3)=[O:19])[S:3][C:4]=2[CH:10]=[C:9]([F:11])[CH:8]=1

Participants

3

Reactant 2

HCID 682422-Furancarbonyl chlorideHCID 7374064,6-Difluoro-1,3-benzothiazol-2-amine

Product 1

HCID 2385407N-(4,6-difluoro-1,3-benzothiazol-2-yl)furan-2-carboxamide

Procedure

Using 2-amino-4,6-difluoro-benzothiazole and furan-2-carboxylicacid chloride the title compound was prepared as a grey solid (81% yield), MS: m/e=280 (M+).

Sources & evidence

ORD record
ord-31e5eaed27fa4e479744c961c64e0fa9
Source dataset
uspto-grants-2003_02
Patent number
US06521754B2

Linked notes

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