2-Amino-5-bromopyridine → 4-(6-Aminopyridin-3-yl)benzoic acid
Reaction equation
Br[C:2]1[CH:3]=[CH:4][C:5]([NH2:8])=[N:6][CH:7]=1.[C:9]([C:12]1[CH:17]=[CH:16][C:15](B(O)O)=[CH:14][CH:13]=1)([OH:11])=[O:10]>>[NH2:8][C:5]1[CH:4]=[CH:3][C:2]([C:15]2[CH:16]=[CH:17][C:12]([C:9]([OH:11])=[O:10])=[CH:13][CH:14]=2)=[CH:7][N:6]=1Participants
3
Procedure
In a similar manner to Example 2 except for the use of 5-bromo-2-aminopyridine and 4-carboxyphenyboronic acid as the raw materials instead, the reaction was conducted, whereby 4-(2-aminopyridin-5-yl)benzoic acid was obtained.
Sources & evidence
- ORD record
- ord-59d26e427d9e478c8f0bc8eeb5c27f90
- Source dataset
- uspto-grants-2003_02
- Patent number
- US06525042B1
Reaction notes
Loading…