1,2-Octanediol → Thieno[3,4-b]-1,4-dioxin, 2-hexyl-2,3-dihydro-

Reaction equation

[CH3:1][O:2][C:3]1[C:7]([O:8][CH3:9])=[CH:6][S:5][CH:4]=1.[CH2:10](O)[CH:11](O)[CH2:12][CH2:13][CH2:14][CH2:15]CC>>[CH2:10]([CH:1]1[O:2][C:3]2=[CH:4][S:5][CH:6]=[C:7]2[O:8][CH2:9]1)[CH2:11][CH2:12][CH2:13][CH2:14][CH3:15]

Participants

Reactant 2

HCID 142311,2-Octanediol

HCID 36135013,4-Dimethoxythiophene

Product 1

HCID 9899382Thieno[3,4-b]-1,4-dioxin, 2-hexyl-2,3-dihydro-

Procedure

Racemic 2-n-hexyl-2,3-dihydro-thieno[3,4-b][1,4]dioxine was synthesized by transetherification of 3,4-dimethoxythiophene with racemic 1,2-octanediol as described in EXAMPLE 1. It was characterized by GC-MS and 1H-NMR-spectroscopy, and exhibited no optical rotation.

Sources & evidence

ORD record: ord-6b01b300406b47048991d30fbf312366
Source dataset: uspto-grants-2006_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07094865B2

Reaction notes

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