Tert-butyl 4-isopropyl-2-nitrophenylcarbamate → Tert-butyl 2-amino-4-isopropylphenylcarbamate
Reaction equation
[C:1]([O:5][C:6](=[O:20])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([CH:14]([CH3:16])[CH3:15])=[CH:10][C:9]=1[N+:17]([O-])=O)([CH3:4])([CH3:3])[CH3:2]>[Pd]>[C:1]([O:5][C:6](=[O:20])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([CH:14]([CH3:15])[CH3:16])=[CH:10][C:9]=1[NH2:17])([CH3:3])([CH3:2])[CH3:4]Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
Prepared from (4-isopropyl-2-nitro-phenyl)-carbamic acid tert.-butyl ester (Example A2) by catalytic hydrogenation with Pd/C according to the general procedure G (method a). Obtained as a white solid (12.59 g).
Sources & evidence
- ORD record
- ord-73a9e6c2a89d430db21cb09b5f89b085
- Source dataset
- uspto-grants-2005_11
- Patent number
- US06960578B2
Reaction notes
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