N-acetyl-2-(triphenylmethylthio)acetamide → N-methyl-N-acetyl-2-(benzylthio)acetamide

Reaction equation

[C:1]([NH:4][C:5](=[O:27])[CH2:6][S:7][C:8]([C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)(C1C=CC=CC=1)C1C=CC=CC=1)(=[O:3])[CH3:2].[C:28](NC(=S)CCC1C=CC=CC=1)(=O)C>>[C:1]([N:4]([CH3:28])[C:5](=[O:27])[CH2:6][S:7][CH2:8][C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1)(=[O:3])[CH3:2]

Participants

Reactant 2

HCID 12837901N-acetyl-2-(triphenylmethylthio)acetamide

HCID 86737130N-acetyl-2-benzylthio acetamide

Product 1

HCID 20540314N-methyl-N-acetyl-2-(benzylthio)acetamide

Procedure

Employing the procedure described above, but substituting for the N-acetyl-2-(triphenylmethylthio) acetamide an equivalent amount of N-acetyl-2-benzylthio acetamide, there is produced N-acetyl-N-methyl-2-(benzylthio) acetamide.

Sources & evidence

ORD record: ord-50de73262d534df8a4acb790f3f62062
Source dataset: uspto-grants-1982_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04329363

Reaction notes

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