Sodium Hydroxide → Methyl 2-benzylidene-3-hydroxypropionate

HRID 1066459

Reaction equation

HRID 1066459 reaction equation
[CH:1](=[C:8]([CH2:13][O:14]C(=O)C)[C:9]([O:11][CH3:12])=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[OH-].[Na+]>CO>[CH:1](=[C:8]([CH2:13][OH:14])[C:9]([O:11][CH3:12])=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 53678280Methyl 2-[(acetyloxy)methyl]-3-phenylprop-2-enoate

Product 1

HCID 54265908Methyl 2-benzylidene-3-hydroxypropionate

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The crude product (2.1917 g) of methyl 2-benzylidene-3-acetoxypropionate obtained in Example 13 was dissolved in 15 ml of methanol, and 84 mg (97%, 2.04 mmols) of sodium hydroxide were added thereto. The mixture was stirred at room temperature for 4 hours to form methyl 2-benzylidene-3-hydroxypropionate.

Sources & evidence

ORD record
ord-c62619cd183b43d4b504d2fff2143bda
Source dataset
uspto-grants-2001_06
Patent number
US06242635B1

Linked notes

Loading…