5-Chloro-2-fluorobenzaldehyde → 5-Chloro-2-fluorobenzyl alcohol
Reaction equation
FC1C=CC(C)=CC=1CO.[F:11][C:12]1[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][C:13]=1[CH:14]=[O:15]>>[F:11][C:12]1[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][C:13]=1[CH2:14][OH:15]Participants
3
Procedure
The title intermediate was prepared essentially as was 2-fluoro-5-methylbenzyl alcohol, supra, except that an equimolar amount of 2-fluoro-5-chlorobenzaldehyde was employed instead of the 2-fluoro-5-methylbenzaldehyde employed therein.
Sources & evidence
- ORD record
- ord-9945f084e6ee4d7c8efc3743e94d4605
- Source dataset
- uspto-grants-2001_06
- Patent number
- US06245761B1
Reaction notes
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