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Tyramine → Nalpha-Benzyl-Ndelta-Boc-Nalpha-Methylornithine 2-(4-Hydroxyphenyl)ethylamide

HRID 1067075
Notes
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Reaction equation

HRID 1067075 reaction equation
[CH2:1]([N:8]([CH3:24])[C@H:9]([C:21]([OH:23])=O)[CH2:10][CH2:11][CH2:12][NH:13][C:14]([O:16][C:17]([CH3:20])([CH3:19])[CH3:18])=[O:15])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[OH:25][C:26]1[CH:31]=[CH:30][C:29]([CH2:32][CH2:33][NH2:34])=[CH:28][CH:27]=1>>[OH:25][C:26]1[CH:31]=[CH:30][C:29]([CH2:32][CH2:33][NH:34][C:21](=[O:23])[C@H:9]([CH2:10][CH2:11][CH2:12][NH:13][C:14]([O:16][C:17]([CH3:18])([CH3:19])[CH3:20])=[O:15])[N:8]([CH2:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)[CH3:24])=[CH:28][CH:27]=1
ParticipantsProcedureWorkupSources & evidenceReaction notes

Participants

3

Reactant 2

HCID 5610TyramineHCID 57299805Nalpha-benzyl-Ndelta-Boc-Nalpha-methylornithine

Product 1

HCID 131722651Nalpha-Benzyl-Ndelta-Boc-Nalpha-Methylornithine 2-(4-Hydroxyphenyl)ethylamide

Procedure

This compound is prepared using Procedure C by coupling of Nα-benzyl-Nδ-Boc-Nα-methylornithine and (4-hydroxyphenyl)ethylamine.

Workup

  1. customThis compound is prepared

Sources & evidence

ORD record
ord-785249db737f4ac6a7c45223decded0f
Source dataset
uspto-grants-2001_06
DOI
10.6084/m9.figshare.5104873.v1
Patent number
US06245746B1

Reaction notes

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On this pageParticipantsProcedureWorkupSources & evidenceReaction notes