4-Ethoxybenzoic acid → 3-BROMO-4-ETHOXYBENZOIC ACID
Reaction equation
[CH2:1]([O:3][C:4]1[CH:12]=[CH:11][C:7]([C:8]([OH:10])=[O:9])=[CH:6][CH:5]=1)[CH3:2].[Br:13]Br>C(Cl)(Cl)Cl>[Br:13][C:5]1[CH:6]=[C:7]([CH:11]=[CH:12][C:4]=1[O:3][CH2:1][CH3:2])[C:8]([OH:10])=[O:9]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
To a solution of 4ethoxybenzoic acid (3.6 g, 0.022 mol) in chloroform (60 ml) was added bromine (1.13 ml, 0.022 mol) in chloroform (20 ml) dropwise. After stirring overnight at room temperature the precipitate was filtered off and dried to afford the title compound as a white solid.
Workup
- filtrationwas filtered off
- customdried
Sources & evidence
- ORD record
- ord-f98146b56e02444fa978c9f341886fd9
- Source dataset
- uspto-grants-2001_06
- Patent number
- US06248754B1
Reaction notes
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