Formaldehyde → N-(hydroxymethyl)benzamide

HRID 1075324

Reaction equation

[C:1]([NH2:9])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:10]=[O:11]>>[OH:11][CH2:10][NH:9][C:1](=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 712Formaldehyde

HCID 2331Benzamide

Product 1

HCID 80493N-(hydroxymethyl)benzamideYield 84%

Procedure

The compound N-(hydroxymethyl)benzamide is prepared in 84% yield from benzamide and formaldehyde using the procedure described by Monti, Gazz. Chim., 50: 39 (1930).

Sources & evidence

ORD record: ord-0cea058cc215435a94db60ef026316b5
Source dataset: uspto-grants-1983_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04395577

Linked notes

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