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Benzylamine → HCID 54545864, compound

HRID 1076964
Notes
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Reaction equation

HRID 1076964 reaction equation
C1SC=CC=1CNC1C=C(C(O)=[O:15])C=C(S(=O)(=O)N)C=1C1C=CC=CC=1.ClC1C=C(C2C=CC=CC=2)C(S(=O)(=O)N)=CC=1C(O)=O.C1(CN)SC=CC=1.[CH2:54]([NH:61][C:62]1[CH:63]=[C:64]([C:75]2[CH:80]=[CH:79][CH:78]=[CH:77][CH:76]=2)[C:65]([S:71](=[O:74])(=[O:73])[NH2:72])=[CH:66][C:67]=1[C:68]([OH:70])=[O:69])[C:55]1[CH:60]=[CH:59][CH:58]=CC=1.C(N)C1C=CC=CC=1>>[CH2:54]([NH:61][C:62]1[CH:63]=[C:64]([C:75]2[CH:76]=[CH:77][CH:78]=[CH:79][CH:80]=2)[C:65]([S:71](=[O:73])(=[O:74])[NH2:72])=[CH:66][C:67]=1[C:68]([OH:70])=[O:69])[C:55]1[O:15][CH:58]=[CH:59][CH:60]=1
ParticipantsProcedureSources & evidenceReaction notes

Participants

6

Reactant 5

HCID 7504BenzylamineHCID 34005(2-Thienylmethyl)amineHCID 21535441HCID 21535441, compoundHCID 21535447HCID 21535447, compound2×HCID 21535449HCID 21535449, compound

Product 1

HCID 54545864HCID 54545864, compound

Procedure

3-thenylamino-6-sulfamoyl-biphenyl-4-carboxylic acid from 3-chloro-6-sulfamoyl-biphenyl-4-carboxylic acid and thenylamine; m.p. 214° - 216°C. (decomp.); yield 37% of theory; and 3-benzylamino-6-sulfamoyl-biphenyl-4-carboxylic acid from 3-chloro-6-sulfamoyl-biphenyl-4-carboxylic acid and benzylamine: m.p. 225° - 227°C. (decomp.); yield 53% of theory.

Sources & evidence

ORD record
ord-00a5076494274aaf953daec8908dcd39
Source dataset
uspto-grants-1976_05
DOI
10.6084/m9.figshare.5104873.v1
Patent number
US03959261

Reaction notes

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On this pageParticipantsProcedureSources & evidenceReaction notes