Ammonia → Maleamic acid

HRID 1078468

Reaction equation

HRID 1078468 reaction equation
[NH3:1].[C:2]1(=[O:8])[O:7][C:5](=[O:6])[CH:4]=[CH:3]1>>[C:2]([OH:7])(=[O:8])/[CH:3]=[CH:4]\[C:5]([NH2:1])=[O:6].[C:2]([OH:7])(=[O:8])/[CH:3]=[CH:4]/[C:5]([NH2:1])=[O:6]

Participants

4

Reactant 2

HCID 222AmmoniaHCID 7923Maleic Anhydride

Product 2

HCID 5280451Maleamic acidHCID 5364140(2E)-3-carbamoylprop-2-enoic acid

Procedure

Components (a) and (b) can also be reacted in a system in which a liquid phase exists in addition to one or more solid phases. This takes place, for example, by reacting gaseous amines or ammonia with molten maleic anhydride. This reaction is carried out in the range from about 50 to 100° C. In this case, component (b) is added at a rate such that the temperature does not rise above 100° C. Several solid products are formed in the reaction, such as maleamic acid, fumaramic acid or their ammonium salts. After completion of the reaction, the products are in the form of powdered solids, and no liquid phase then exists.

Workup

  1. additionexists in addition to one or more solid phases
  2. customis carried out in the range from about 50 to 100° C
  3. customdoes not rise above 100° C

Sources & evidence

ORD record
ord-04dcd777d6014ec5a388c63b547c6686
Source dataset
uspto-grants-1996_08
Patent number
US05548036

Linked notes

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